Driving research of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS),
Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Post COVID .

Melbourne ME/CFS Collaboration

Precision personalized medicine research program for Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS)

Core Aims

What we hope to achieve

Our Philosophy

Our fundamental philosophy

Science Team

List of scientific collaborators

The Research

Current research projects

About the Melbourne ME/CFS Collaboration

Established in 2020, the Melbourne ME/CFS Collaboration is directed by Christopher W. Armstrong, PhD.

The Melbourne ME/CFS Research Collaboration seeks to develop a disease management and treatment approach that focuses on the individual patient and the biology that underlies their disease. Their research will look for unifying biological pathways of ME/CFS that cause the disease experience to be the same between patients while also identifying biological aspects that produce different disease experiences between patients.

About Chris Armstrong, PhD

Chris Armstrong, PhD, is most well known for his research using metabolomics to observe biochemical alterations in ME/CFS patients. He began his work in this field at the University of Melbourne, beginning a PhD project to apply metabolomics to study Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and published his first ME/CFS metabolomics study on blood and urine in 2015.

Since then Chris has set up collaborative efforts to apply metabolomics to immunological experiments on ME/CFS, observing how metabolism may relate to immune cell function. He has also focused on longitudinal research in ME/CFS while looking to extend metabolic capabilities across the field of ME/CFS to help collate different patient groups.

Core Aims

Fundamental Philosophy

Current Studies Under Review

Nitrogen Metabolism and Testing Nitrogen Hypothesis in ME/CFS

Nitrogen Metabolism and Testing Nitrogen Hypothesis in ME/CFS STUDY AIM This project aims to test the nitrogen hypothesis, which is that damaging, nitrogen-containing by-products of …

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Pediatrics ME/CFS Deep Omics Profiling and Longitudinal Study

Pediatrics ME/CFS Deep Omics Profiling and Longitudinal Study STUDY AIM This proposal seeks to understand pathological mechanisms of paediatric ME/CFS (13 to 18 years old) …

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Characterizing B cells in ME/CFS

Characterizing B cells in ME/CFS STUDY AIM This study aims to broadly evaluate B cell subsets, metabolism, viability, receptors, and antibodies in people with ME/CFS. …

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Developing Condensed Precision Medicine Protocol for ME/CFS

Developing Condensed Precision Medicine Protocol for ME/CFS PROTOCOL AIM Establish a condensed personalized research protocol that can be used to characterize ME/CFS in individual patients …

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Developing Rapid System for Outlier Analysis in ME/CFS

Developing Rapid System for Outlier Analysis in ME/CFS PROTOCOL AIM Establish an analytical workflow for outlier analysis in ME/CFS to identify disease or symptom exacerbators …

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CRC Collaborators

To carry out these ambitious projects, Dr. Armstrong is establishing networks and collaborations extending to USA, UK, Sweden, and other Australian institutions. 

University of Melbourne, Australia

Christopher Armstrong, PhD

Paul Gooley, PhD

Neil McGregor, PhD

David Ascher, PhD

Elisha Josev, PhD

Sarah Knight, PhD

Adam Scheinberg, MD

David Stroud, PhD

Stanford University, USA

Ronald Davis, PhD

Robert Phair, PhD

Laurel Crosby, PhD

Julie Wilhelmy

Amit Saha, PhD

Layla Cervantes

Anna Okumu

Mike Snyder, PhD

Uppsala University, Sweden

Jonas Bergquist, MD, PhD

Massachusetts General Hospital, USA

Ronald Tompkins, MD, ScD

Wenzhong Xiao, PhD

Michael VanElzakker, PhD

University of Montreal, Canada

Alain Moreau, PhD

Open Medicine Foundation

Linda Tannenbaum

UC San Diego, USA

Robert Naviaux, MD, PhD

University of Alabama Birmingham, USA

Jarred Younger, PhD

University College London, UK

Jo Cambridge, PhD

La Trobe University, Australia

Sarah Annesley, PhD

Paul Fisher, PhD

Daniel Missailidis

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