Regulation of the Itaconate Shunt in ME/CFS
This project aims to characterize the mitochondrial function in whole peripheral blood mononuclear cells (PBMCs) in ME/CFS.
Copyright © 2025 Open Medicine Foundation. All Rights Reserved.
The ME/CFS Collaborative Research Center (previously known as the CFS Research Center) at Stanford University was established in 2014 and is part of the Stanford Genome Technology Center. Both centers are directed by Ronald W. Davis, PhD, Professor of Biochemistry and of Genetics at Stanford.
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Throughout his career, Dr. Davis has conducted cutting edge, innovative, interdisciplinary research and technology development on cancer, immunology, genetics, infectious disease, novel drug development, and nanofabrication of diagnostic instruments.
Dr. Davis was the first to physically map the genome of any organism (1968).
Dr. Davis discovered a simple way to join together DNA from two organisms (“sticky ends”) and was the first to generate a hybrid DNA molecule that could replicate inside of cells (DNA cloning).
This project aims to characterize the mitochondrial function in whole peripheral blood mononuclear cells (PBMCs) in ME/CFS.
This project aims to develop and use a platform that can evaluate neutrophil dysfunction in ME/CFS.
This project aims to characterize viral factors associated with immune responses and inflammation in ME/CFS.
The goal of the project is to develop, characterize, and validate a microfluidic chip for the estimation of biomechanical properties of red blood cells (RBCs) isolated from ME/CFS patients vis-à-vis healthy controls.
This project aims to test whether genetic markers and other indicators of BH4 deficiency are also present in subjects with Long COVID.
This technology demonstrates a significant difference between ME / CFS patients and healthy controls.
The goal of this study was to extend the Severely ill Patient Study and conduct a comprehensive “Big Data” analysis on ME/CFS patients and their families.
Director
Ronald W. Davis, PhD, Professor of Biochemistry and Genetics, Stanford University School of Medicine; Director, Stanford Genome Technology Center; Director, Chronic Fatigue Syndrome Research Center at Stanford University; Chair, Open Medicine Foundation ME/CFS Scientific Advisory Board.
Collaborative Research Center / Stanford Genome Technology Center
Robert Phair, PhD
Wenzhong Xiao, PhD
Mohsen Nemat-Gorgani, PhD
Peidong Shen, PhD
Laurel Crosby, PhD
Michael Jensen
Fereshteh Jahaniani, PhD
Gozde Durmus, PhD
Julie Wilhelmy
Alex Kashi
Anand Ramasubramanian, PhD
Amit Saha, PhD
Layla Cervantes
Ami Mac, MD
David Kaufman, MD
Bela Chheda, MD
Chris Armstrong, PhD
Katrina Hong
Anna Okumu
Ashley Haugen
Collaborators
Juan Santiago, PhD
Eric Shaqfeh, PhD
Mark M. Davis, PhD
Michael Sikora
Mike Snyder, PhD
Craig Heller, PhD
Lars Steinmetz, PhD
Jonas Bergquist, MD, PhD
Rahim Esfandyarpour, PhD
Curt Scharfe, MD
Robert Naviaux, MD, PhD
William Robinson, MD
Lucinda Bateman, MD
Jennifer Frankovich, MD
In Memoriam – Ron Tompkins, MD, ScD
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