The only relief I’ve had from my fatigue in the past ten years was once in 2012 during a week long course of 50mg/day prednisone, and for a week last year following a stellate ganglion block procedure for PTSD. . Both of these interventions have a profound effect on the HPA axis, which leads me to believe HPA axis dysregulation is the root cause of my chronic fatigue. Is there any evidence that ME / CFS is primarily a stress disorder?
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