Driving research of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS),
Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Post COVID .

A Cure Is Out There

People with Chronic Complex Diseases deserve the right to live full, productive lives.

A Game Changer

OMF's goal is to raise $20+ million per year, in honor of the over 20 million ME / CFS sufferers worldwide.

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Advisory Board
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An Alliance of
Brilliant Scientific Minds

18 World-renowned scientists

2 Nobel Laureates

5 National Academy of Sciences Members

World-Class Research

5 OMF established ME / CFS Collaborative Research Centers

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OMF Awarded Score of 100
on Charity Navigator!

OMF’s score of 100 serves as an indicator of trust, demonstrating our longstanding commitment to ensuring accountability, transparency, and measures of financial health, including stability, efficiency and sustainability.

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OMF ACCELERATES RESEARCH ACROSS THE GLOBE

Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) affects over 20 million people.

Established in 2012, Open Medicine Foundation (OMF) leads the largest, concerted worldwide nonprofit effort to diagnose, treat, and  prevent ME / CFS and related chronic, complex diseases such as Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Post COVID.

OMF adds urgency to the search for answers by driving transformational philanthropy and investments into global research. We have raised over $28 Million from private donors, and facilitated and funded the establishment of five prestigious ME / CFS Collaborative Research Centers.

OMF Funded Collaborative Research Centers

at Stanford

Ronald W. Davis, PhD
Director

Innovative, collaborative, multi-disciplinary research

Ronald G. Tompkins, MD, ScD
Wenzhong Xiao, PhD
Co-Directors

Clinical and scientific mechanistic studies towards discovering new treatments

at Uppsala, Sweden

Jonas Bergquist, MD, PhD
Director

Research for biomarkers in body and brain

Chris Armstrong, PhD
Director

Precision personalized medicine research program

POST COVID-19 TO ME/CFS RESEARCH PLAN

The current COVID-19 pandemic offers an unprecedented opportunity to understand how a viral infection may convert to ME/CFS in some patients.

The five ME/CFS Collaborative Centers have begun a unique,  extensive, in-depth longitudinal molecular study following COVID-19 patients. Their shared goal is to determine the pathways involved in maintaining long-term symptoms in some patients,  possibly converting to ME/CFS. They seek to learn about these pathways so as to develop biomarkers, novel drug targets,  new treatment, and prevention strategies.

OMF Scientific Advisory Board

18 world-renowned scientists

2 Nobel laureates

5 National Academy
of Sciences members

View our latest news

Post-COVID Syndrome to ME/CFS

In 2020, OMF secured a $1 million grant to launch the first year of an international, multi-year study across the five OMF funded Collaborative Research Centers (CRC). The aim of this study is to examine Post-COVID Syndrome transitioning to ME/CFS. We are actively working to raise an additional $2 million for years two and three of the study. I am pleased to share with you an update on the first phase of this groundbreaking — and urgently needed — research project.

Research Project Tests and Terms

Post-COVID Syndrome to ME/CFS Research Study Summarized Definitions of Current and Future Project Tests and Terms Autoantibodies Antibodies that react with self-molecules and that occur

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Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia Leading Research. Delivering Hope.Open Medicine Foundation®

 

Averting a second pandemic:

Open Medicine Foundation leads groundbreaking international study of

Long COVID’s conversion to ME/CFS

AGOURA HILLS, CALIF.  — Open Medicine Foundation (OMF) is leading a large-scale international collaborative study investigating the potential conversion of Post-Acute Sequelae SARS-CoV-2 infection — more commonly known as Long COVID or Post-COVID Syndrome —  to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), a chronic, life-altering disease with no known cause, diagnostic test or FDA approved treatments available.

Up to 2.5 million people in the U.S. alone suffer from ME/CFS; the COVID-19 pandemic could at least double that number. An estimated 35 percent of Americans who had COVID-19 have failed to fully recover several months after infection, prompting many to call it “a potential second pandemic.”

OMF recognized a familiar health crisis emerging, one with eerie similarities to ME/CFS. This crisis presented a unique opportunity to understand how a viral infection — in this case COVID-19 — may develop into ME/CFS in some patients. The goal is to find targeted treatments for ME/CFS patients and ultimately prevent its onset in people infected with SARS-CoV-2 or other infections.

The federal government is only now investing in Post-COVID research, with no focus on its connection to ME/CFS. OMF has already engaged researchers for the largest-scale study of its kind, solely supported by private donors who have contributed over one million dollars to date. When fully funded, the five million dollar, three-year study will be conducted across the globe at OMF funded Collaborative Research Centers, led by some of the world’s top researchers and ME/CFS experts.

BACKGROUND

In a significant percentage of patients, infections preceded their development of ME/CFS.  For example, according to the CDC about one in ten infected with Epstein-Barr virus, Ross River virus, or Coxiella burnetti develop symptoms that meet the criteria for ME/CFS.

THE STUDY

The ability to follow the development of ME/CFS from a known viral infection is unprecedented to date and crucial to researchers’ understanding of the disease. The focus of this study is to find the biological differences between persons returning to good health after COVID-19 and persons who remained ill more than six months after infection and developed ME/CFS.  Understanding these alterations in key pathways can lead to groundbreaking discoveries including new biomarkers, drug targets, and prevention and treatment strategies.

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About Open Medicine Foundation

Established in 2012, Open Medicine Foundation leads the largest, concerted worldwide nonprofit effort to diagnose, treat, and prevent ME/CFS and related chronic, complex diseases such as Post Treatment Lyme Disease Syndrome, Fibromyalgia, and Post COVID. OMF adds urgency to the search for answers by driving transformational philanthropy into global research. We have raised over $28 Million from private donors and facilitated and funded the establishment of five prestigious ME/CFS Collaborative Research Centers around the world. To learn more, visit www.omf.ngo.

CONTACT:

Heather Ah San

Development and Communications Manager

1-650-242-8669

heather@omf.ngo