Driving research of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS),
Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Post COVID .

Ronald G. Tompkins, MD, ScD
Chief Medical Officer – Open Medicine Foundation
Co-Director – The Harvard ME/CFS Collaboration at the Harvard Affiliated Hospitals

Sumner M. Redstone Professor of Surgery, Harvard Medical School

Founding Director, Center for Surgery, Innovation & Bioengineering, Massachusetts General Hospital

Dr. Ronald Tompkins’s work in the genomics, proteomics, and ultrastructural roles in inflammation and metabolism promises to discover underlying mechanisms of ME / CFS, and his leadership in multidisciplinary, multi-institutional large research projects will energize OMF’s efforts to ignite Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) research across the globe.

Dr. Tompkins is widely recognized for his work in translational science, medicine, and engineering. He graduated from Tulane University in 1972 and Tulane School of Medicine in 1976. During his training in surgery at the MGH, Dr. Tompkins earned a Doctorate in chemical engineering at Massachusetts Institute of Technology (MIT). He completed his Harvard surgery residency and joined the surgical faculty at MGH in 1987. He served as Chief of Trauma and Burn Services at the MGH and Chief of Staff at the Boston’s Shriners Hospital for 22 years.

Dr. Tompkins has led a fundamental and clinical research program that began in 1990, with an NIH-supported first-in-the-nation Specialized Research Center in trauma.  It’s associated Trauma Research Training Program has produced dozens of the current leaders in the clinical and research field of injury. In 2001, he led a large-scale Collaborative Research Program in injury research, which was the largest NIH-funded program ever received by MGH and the 10th largest NIH extramural program to date nationally. These programs – with well more than $200M in public funding – have provided Dr. Tompkins with a unique understanding of inflammation and metabolic features of humans in response to severe stresses.

Following these decades of significant clinical and basic science discovery, Dr. Tompkins founded a center for research and innovation, which has translated scientific applications into multiple inventions and companies. Three previous companies eventually sold for a total of more than $1.2B. He currently serves on the Boards of Directors of start-up companies in a vast array of medical applications involving Treatment for Alzheimer’s Disease, Point-of-Care Diagnostics, Chimeric Antigen Receptor (CAR) T-cell Therapies, Microcirculatory Dysfunction in the Critically Ill, and Novel Approaches to Cellular Function Ex Vivo.

Dr. Tompkins has served on dozens of Scientific, Not-for-Profit, and Academic Boards and National Committees and has published more than 500 research contributions in medicine and engineering journals toward the advancement of science and engineering in medicine. He has delivered over 500 invited keynote and scientific meeting presentations, lectures as well as he has received numerous honors and awards.

 

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Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia Leading Research. Delivering Hope.Open Medicine Foundation®

 

Averting a second pandemic:

Open Medicine Foundation leads groundbreaking international study of

Long COVID’s conversion to ME/CFS

AGOURA HILLS, CALIF.  — Open Medicine Foundation (OMF) is leading a large-scale international collaborative study investigating the potential conversion of Post-Acute Sequelae SARS-CoV-2 infection — more commonly known as Long COVID or Post-COVID Syndrome —  to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), a chronic, life-altering disease with no known cause, diagnostic test or FDA approved treatments available.

Up to 2.5 million people in the U.S. alone suffer from ME/CFS; the COVID-19 pandemic could at least double that number. An estimated 35 percent of Americans who had COVID-19 have failed to fully recover several months after infection, prompting many to call it “a potential second pandemic.”

OMF recognized a familiar health crisis emerging, one with eerie similarities to ME/CFS. This crisis presented a unique opportunity to understand how a viral infection — in this case COVID-19 — may develop into ME/CFS in some patients. The goal is to find targeted treatments for ME/CFS patients and ultimately prevent its onset in people infected with SARS-CoV-2 or other infections.

The federal government is only now investing in Post-COVID research, with no focus on its connection to ME/CFS. OMF has already engaged researchers for the largest-scale study of its kind, solely supported by private donors who have contributed over one million dollars to date. When fully funded, the five million dollar, three-year study will be conducted across the globe at OMF funded Collaborative Research Centers, led by some of the world’s top researchers and ME/CFS experts.

BACKGROUND

In a significant percentage of patients, infections preceded their development of ME/CFS.  For example, according to the CDC about one in ten infected with Epstein-Barr virus, Ross River virus, or Coxiella burnetti develop symptoms that meet the criteria for ME/CFS.

THE STUDY

The ability to follow the development of ME/CFS from a known viral infection is unprecedented to date and crucial to researchers’ understanding of the disease. The focus of this study is to find the biological differences between persons returning to good health after COVID-19 and persons who remained ill more than six months after infection and developed ME/CFS.  Understanding these alterations in key pathways can lead to groundbreaking discoveries including new biomarkers, drug targets, and prevention and treatment strategies.

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About Open Medicine Foundation

Established in 2012, Open Medicine Foundation leads the largest, concerted worldwide nonprofit effort to diagnose, treat, and prevent ME/CFS and related chronic, complex diseases such as Post Treatment Lyme Disease Syndrome, Fibromyalgia, and Post COVID. OMF adds urgency to the search for answers by driving transformational philanthropy into global research. We have raised over $28 Million from private donors and facilitated and funded the establishment of five prestigious ME/CFS Collaborative Research Centers around the world. To learn more, visit www.omf.ngo.

CONTACT:

Heather Ah San

Development and Communications Manager

1-650-242-8669

heather@omf.ngo