To explore the hypothesis that deranged flow of the cerebrospinal fluid (CSF) due to craniocervical obstructions and/or instability may cause deranged intracranial pressure (ICP), neuroinflammation and cardinal symptoms of ME/CFS.
Our study will be the first to systematically measure CNS structural abnormalities in a large ME/CFS case-control study using gold-standard methods. It will Highlight CSF pressure, structural abnormalities, and neuroinflammation, with pathophysiological implementations in ME/CFS. Added to this will be collected biospecimens to perform extensive state-of-the art analyses with the ambition to identify diagnostic and prognostic biomarkers
The IRB review will kick off shortly.
The overall aim is to explore the hypothesis that deranged flow of the cerebrospinal fluid (CSF) due to craniocervical obstructions and/or instability may cause deranged intracranial pressure (ICP), neuroinflammation and cardinal symptoms of ME/CFS. If this hypothesis proves true it opens a new research area in ME/CFS and hopes for effective treatment to regulate ICP and relieve symptoms associated with ME/CFS. This study will make use of CNS imaging and analysis of CSF, blood, saliva samples, and will identify proteomic and metabolomic biomarkers of the disease, a highly needed tool in the diagnostic and prognostic process. By the combination of more detailed clinical examination and evaluation and multiOmics biomarker analysis we will be able to provide a more individually adapted care and hopefully cure.
What are the advantages of giving from your Donor Advised Fund (DAF)?
How do I make a donation through my DAF?
Just click on the DAF widget below. It is simple and convenient to find your fund among the over 900 funds in our system.
Still can’t find your fund?
Gifting of Stock
DTC #: 0164
Account #: 47083887
Account Registered as:
Open Medicine Foundation
29302 Laro Drive
Agoura Hills, CA 91301
Please speak to your personal tax advisor and then call OMF at 650-242-8669 to notify us of your donation or with any questions.