Copyright © 2023 Open Medicine Foundation. All Rights Reserved.
This project aims to explore the biological changes that occur in the muscles during Post-exertional Malaise (PEM).
The skeletal muscle genomics have been completed and the analysis is underway to include metabolic modeling
Post Exertional Malaise (PEM) is the key feature of ME/CFS, given the extensive characterization of muscle exertion and recovery in healthy people, the evaluation may indicate how the disease perpetuates.
The hypothesis is that the inflammation-related recovery mechanisms become dysfunctional in the ME/CFS disease, and this dysregulation causes a delayed recovery of muscle after exertional stress.
Muscle biopsy samples will be taken from ME/CFS patients both at rest and eventually during their recovery from mild to moderate muscular stress. Comparisons will be made to healthy volunteers also at rest, during recovery from muscular stress, and during immobilization.
Using muscle samples, this study will examine the following:
Genomics
Open Medicine Foundation®
29302 Laro Drive, Agoura Hills, CA 91301 USA
Phone: 650-242-8669
Copyright © 2023 Open Medicine Foundation. All Rights Reserved.
What are the advantages of giving from your Donor Advised Fund (DAF)?
How do I make a donation through my DAF?
Just click on the DAF widget below. It is simple and convenient to find your fund among the over 900 funds in our system.
Still can’t find your fund?
Donate your appreciated stock directly to OMF and you can receive an immediate income-tax deduction for the fair market value of the securities on the date of transfer (even if you originally paid much less for them).Gifting of Stock
Broker: Schwab
DTC #: 0164
Account #: 47083887
Account Registered as:
Open Medicine Foundation
29302 Laro Drive
Agoura Hills, CA 91301
Please speak to your personal tax advisor and then call OMF at 650-242-8669 to notify us of your donation or with any questions.