List of Tests in ME/CFS Severely ill-BIG DATA Study

Our ME/CFS Severely ill-BIG DATA Study is Phase I in our End ME/CFS Project. This part includes a comprehensive/extensive testing of severely ill patients. By thoroughly checking blood, urine, and other body products, we expect to find biological abnormalities that could explain the debilitating symptoms. We don’t want to miss anything. So we’re doing it completely the first time:

Research Tests

  • RNA Gene Expression – PBMCs
  • RNA Gene Expression – NKs
  • RNA Gene Expression – Monocytes
  • RNA Gene Expression – T-Cells
  • RNA Gene Expression – B-Cells
  • RNA Gene Expression – Macrophages
  • RNA Gene Expression – Dendritic Cells
  • MicroRNA in Plasma
  • Proteomics
  • Cell-Free DNA
  • Whole Genome Sequencing
  • Whole Exome Genome Sequencing
  • Mitochondrial Genome Sequencing
  • Mitochondrial DNA/Nuclear DNA Radio
  • HLA DNA Sequencing
  • WBC density
  • Autoantibody panel
  • T-cell Repertoire DNA Sequencing-Stanford
  • T-cell Repertoire DNA Sequencing-Sequenta
  • CyTOF Standard Panel
  • CyTOF Additional Panels
  • Pan Viral Panel
  • Serum Cytokines
  • Ceres Nano Lyme
  • Microbiome – stool
  • Metabolomics – stool
  • Metabolomics – plasma
  • Metabolomics – urine
  • Heavy Metals – blood
  • Heavy Metals – urine
  • Mycotoxins by Magarray

 

Clinical Testing

  • Acylcarnitines
  • Ammonia
  • Bartonella extended cx
  • Biotin (Vitamin B7)
  • CBC (Complete Blood Count)
  • Chemistry Comprehensive Panel
  • Creatine Kinase
  • Copper
  • C- Reactive Protein
  • Cysteine
  • Folate
  • FSH (Follicle-Stimulating Hormone)
  • LH (Luteinizing Hormone)
  • Estrogen
  • HbA1C (Hemoglobin A1c)
  • Homocysteine
  • IgG Subsets
  • Lactate
  • Lyme Serology with reflex Western Blot
  • Lymphocyte Subsets
  • MMA (Methylmalonic Acid)
  • MTHFR Mutations (Methylenetetrahydrofolate)
  • Natural Killer Cell (Count & Function)
  • Organic Acids – urine
  • Pyruvate
  • Serotonin
  • Testosterone
  • Thyroid Panel
  • Uric Acid
  • Vasopressin/ADH
  • Viral Digital PCR
  • Viral Serologies:
    • EBV EA (Epstein Barr Virus EA)
    • EBV NA (Epstein Barr Virus NA)
    • EBV VCA (Epstein Barr Virus VCA)
    • CMV (Cytomegalovirus)
    • HHV-6 (Human Herpesvirus 6)
    • Parvovirus
    • HHV-7 (Human Herpes Virus 7)
    • HSV1&2 (Herpes Simplex 1 & 2)
  • Vitamin B12 (Cobalamin)
  • Vitamin D25 OH

 

Other Testing/Monitoring

  • Extended EEG
  • Sleep monitoring
  • Fitbit
  • Cognitive Testing
  • Questionnaires – SF36, PROMIS