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ME/CFS and related chronic complex diseases

News

OMF Funded Severely Ill Big Data Study Update

On this #OMFScienceWednesday, we review the Severely ill Big Data Study. This study, led by Drs. Davis and Xiao, included over 1,000 tests per patient, producing, to our knowledge, the biggest dataset ever generated in a cohort of ME/CFS patients. This big data study examined the patients’ genome, gene expression, metabolomics, microbiome, cell-free DNA sequencing...

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Personalized Medicine

This week for #OMFScienceWednesday we look in our archives and re-share with you an earlier post about personalized medicine. In honor of this week’s conference at Stanford University, on this #OMFScienceWednesday we ask the question: what is personalized health? Whether you call it personalized medicine, precision health, or P4 medicine, we are talking about a current revolution...

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Dr. Ron Davis Interviewed by WBUR at MA Dept. of Public Health “Unrest” Screening | ME/CFS Research (Video)

Ronald W. Davis, PhD, a pre-eminent scientist at Stanford and our own scientific advisory board director, in this interview mentions 4 prospective biomarkers, tells of the OMF-funded research now being pursued, and tells of the biological abnormalities being seen in ME/CFS patients. He also gives some advice for healthcare providers. The interviewer is Deborah Becker...

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National DNA Day

Happy #OMFScienceWednesday, and happy National DNA Day! This year’s National DNA Day is a very special one, as it marks the 15th anniversary of the completion of the Human Genome Project. This is a great opportunity for students, teachers, and the public to learn more about how advances in genetics and genomics have changed people’s...

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The hunt for elusive pathogens in ME/CFS

Do infections lead to lasting changes in immune or metabolic function that lead to symptoms, or is the pathogen still present?   This #OMFScienceWednesday, OMF discusses recently funded research into addressing this central question in ME/CFS. Do infections lead to lasting changes in immune or metabolic function that lead to symptoms, is the pathogen still present,...

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RBC shape, RBC deformability

Many of you have been asking questions about our red blood cell research. For this #OMFScienceWednesday, we examine the difference between RBC shape and RBC deformability, and how they relate to blood flow. RBC shape You may have seen an image of a red blood cell (RBC) in the past: it is a small, pink...

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The ‘omes’

Do you know your ‘omes’? For this #OMFScienceWednesday, we look at the ‘omes’ studied in biomedical research, and why we are funding projects to study them in ME/CFS. Genome: The genome refers to all of the DNA in a living thing.  The DNA is organized into genes that code for proteins that have specific jobs...

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OMF-funded research: red blood cell deformability in ME/CFS

On this #OMFScienceWednesday, we present a new project that we are funding that will evaluate the ‘deformability’ of red blood cells as a potential biomarker for ME/CFS. Red blood cells (RBCs) are the most common cells in the blood. Their main role is to transport oxygen and carbon dioxide in the blood, and this role...

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OMF-funded research: a metabolic ‘trap’ hypothesis for ME/CFS

On this #OMFScienceWednesday we highlight a new project that OMF is funding, which proposes a new metabolic ‘trap’ hypothesis for ME/CFS. This project is just getting started under the direction of Dr. Robert Phair, Chief Science Officer of Integrative Bioinformatics, Inc., an expert in computational modelling of biological processes. Dr. Phair has been collaborating with...

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OMF Newsletter – March 2018

Linda Tannenbaum Named 2017 Advocate of the Year There’s an Angel Among Us – Linda Tannenbaum Is Offering Genuine Hope to ME/CFS Patients (Shared from ProHealth) ProHealth is proud to name Linda Tannenbaum, founder of Open Medicine Foundation, as ProHealth’s 2017 ME/CFS Advocate of the Year. ProHealth founder, Rich Carson said, “Linda is a bottomless pit of compassion and...

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