Driving research of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS),
Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Long Covid

Announcing our sixth Research Center!

Triple Giving Tuesday starts today:

Announcing our sixth Research Center!

From the desk of Linda Tannenbaum 
Chief Executive Officer, Open Medicine Foundation

Open Medicine Foundation (OMF) is pleased to share, on the first day of our Triple Giving Tuesday campaign, some exciting research news!

As part of our mission to fund and facilitate urgent, open, and collaborative research, we are excited to announce that we have formally added a sixth center to our international OMF Collaborative Research Network to accelerate computational analysis. 

With Wenzhong Xiao, PhD, as Director, the newly established Computational Research Center for Complex Diseases will analyze and provide critical information and insights into projects being conducted at the other five OMF funded research centers at Stanford, Harvard, Uppsala, Montreal, and Melbourne. 

Please be part of this historic effort by supporting #TripleGivingTuesday today. All gifts received from now until International Giving Tuesday, November 30, 2021, are triple matched, helping us to fast-track research so that we can find treatments and a cure!

Dr. Xiao is a world-renowned expert in computational genomics and the Director of the Immuno-Metabolic Computational Center at Massachusetts General Hospital (MGH), Harvard Medical School. He also leads a Computational Genomics Group at Stanford Genome Technology Center (SGTC). His research is at the intersection of computation, genomics, and medicine.

*Dr. Xiao is currently hiring for computational biologists/bioinformaticians to join his team. If interested, please visit this link to learn more.*

Dr. Xiao explains that the sixth Research Center includes:
  • Bioinformatics and computation, essential to research projects, from study design, performing the research, interpreting the results, and writing publications.
  • Development and application of state-of-the-art algorithms to integrate clinical phenotypes and molecular signatures of ME/CFS to uncover disease mechanisms and identify drug targets.
  • Establishment and maintenance of the OMF funded Data Center platform for open data sharing and online collaboration.

Computational analysis plays an essential role in OMF’s research strategy and the studies being conducted within the Collaborative Research Network. Because of the contributions of generous individuals like you, we can fund these critical efforts to interpret research data — data that is essential to developing diagnostic tools and treatments for millions living with multisystem chronic, complex diseases. 

This #TripleGivingTuesday, generous OMF donors have agreed to TRIPLE match donations up to $600,000. That means when you donate $20, you really donate $60! And you can make a gift any day of the week now through International Giving Tuesday on November 30, 2021.

Your contribution made during the first week of Triple Giving Tuesday will jumpstart our campaign and show your support for cutting edge researchers like Dr. Xiao.  

Donate today to ensure we can take advantage of the entire matching gift amount.

Give any amount, any day of the week — and your gift will be TRIPLED! 

Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia Leading Research. Delivering Hope.Open Medicine Foundation®

What are the advantages of giving from your Donor Advised Fund (DAF)?

  • Your gifts to your donor advised fund entitle you to an immediate income tax deduction at the time of contribution.
  • You avoid capital gains tax on appreciated assets you place in your donor advised fund.
  • Your fund’s investment gains accumulate tax free.
  • Funds are distributed to Open Medicine Foundation in your name and immediately put to use to support our worldwide research efforts.

How do I make a donation through my DAF?

Just click on the DAF widget below. It is simple and convenient to find your fund among the over 900 funds in our system.

Still can’t find your fund? 

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  • You can also designate OMF as a beneficiary for your Donor Advised Fund
  • Questions? Give us a call at 650-242-8669 

Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia Leading Research. Delivering Hope.Open Medicine Foundation®

Averting a second pandemic:

Open Medicine Foundation leads groundbreaking international study of

Long COVID’s conversion to ME/CFS

AGOURA HILLS, CALIF.  — Open Medicine Foundation (OMF) is leading a large-scale international collaborative study investigating the potential conversion of Post-Acute Sequelae SARS-CoV-2 infection — more commonly known as Long COVID or Post-COVID Syndrome —  to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), a chronic, life-altering disease with no known cause, diagnostic test or FDA approved treatments available.

Up to 2.5 million people in the U.S. alone suffer from ME/CFS; the COVID-19 pandemic could at least double that number. An estimated 35 percent of Americans who had COVID-19 have failed to fully recover several months after infection, prompting many to call it “a potential second pandemic.”

OMF recognized a familiar health crisis emerging, one with eerie similarities to ME/CFS. This crisis presented a unique opportunity to understand how a viral infection — in this case COVID-19 — may develop into ME/CFS in some patients. The goal is to find targeted treatments for ME/CFS patients and ultimately prevent its onset in people infected with SARS-CoV-2 or other infections.

The federal government is only now investing in Post-COVID research, with no focus on its connection to ME/CFS. OMF has already engaged researchers for the largest-scale study of its kind, solely supported by private donors who have contributed over one million dollars to date. When fully funded, the five million dollar, three-year study will be conducted across the globe at OMF funded Collaborative Research Centers, led by some of the world’s top researchers and ME/CFS experts.


In a significant percentage of patients, infections preceded their development of ME/CFS.  For example, according to the CDC about one in ten infected with Epstein-Barr virus, Ross River virus, or Coxiella burnetti develop symptoms that meet the criteria for ME/CFS.


The ability to follow the development of ME/CFS from a known viral infection is unprecedented to date and crucial to researchers’ understanding of the disease. The focus of this study is to find the biological differences between persons returning to good health after COVID-19 and persons who remained ill more than six months after infection and developed ME/CFS.  Understanding these alterations in key pathways can lead to groundbreaking discoveries including new biomarkers, drug targets, and prevention and treatment strategies.


About Open Medicine Foundation

Established in 2012, Open Medicine Foundation leads the largest, concerted worldwide nonprofit effort to diagnose, treat, and prevent ME/CFS and related chronic, complex diseases such as Post Treatment Lyme Disease Syndrome, Fibromyalgia, and Post COVID. OMF adds urgency to the search for answers by driving transformational philanthropy into global research. We have raised over $28 Million from private donors and facilitated and funded the establishment of six prestigious ME/CFS Collaborative Research Centers around the world. To learn more, visit www.omf.ngo.


Heather Ah San

Development and Communications Manager